CLINICAL BASE

PCOS is getting a new name, first-ever NHS guidance, and a fresh UK study into GLP-1 medicines. Here's what the research actually shows, and what it means for you right now.

Sleep apnoea and weight-loss medicines are being studied together, with striking trial results. But is tirzepatide actually licensed for sleep apnoea in the UK? Here's what the evidence and the regulators actually say.

Headlines about "hundreds of deaths linked to weight-loss jabs" can be frightening. Here's what the MHRA's Yellow Card safety reports actually show, and what it means if you're considering one of these medicines.

NICE has recommended a weight-loss jab to help prevent repeat heart attacks and strokes — a major new use that goes beyond weight loss itself.

Weight-loss jabs can genuinely help, but 2026 research shows they work best paired with diet, strength training and proper support — not on their own.

Most side effects from weight-loss injections are common and mild, but a few are rare and serious. Here's what to expect, how to cope, and the warning signs that mean you should get help, with the latest MHRA safety advice.

If you've been thinking about weight-loss medication, you've probably heard two names a lot: Wegovy and Mounjaro. Both are injections. Both help people lose weight. But which one works better? For a long time, nobody knew for sure, because the two drugs had never been tested against each other in the same study, on the same people, at the same time. Now they have. And the results tell an interesting story — not just about which drug wins, but about how "winning" isn't always

Weight-loss medicines like Wegovy and Mounjaro are in the news a lot. Many people want to try them. But not everyone can get them, and not everyone should. Clinicians follow careful rules to decide who is a good fit. Let's look at how those rules work, using the UK's NHS as our main example. What Is BMI, and Why Does It Matter? BMI stands for "body mass index." It's a number clinicians calculate using your height and weight. It gives a rough idea of whether someone's weight m

You've probably heard people talking about weight-loss jabs like Wegovy, Mounjaro, or Saxenda. These medicines are called GLP-1 drugs. That's short for a hormone your gut makes called GLP-1 (glucagon-like peptide-1). The drugs copy that hormone to help people feel full sooner and lose weight. But here's something a lot of people don't know: some of these drugs are also given to children and teenagers in the UK. Let's break down what's actually approved, what's happening on th

For years, the most powerful weight-loss medicines in the UK — the GLP-1 drugs you've probably heard of, like Ozempic, Wegovy, and Mounjaro — only came as injections. You had to use a needle to inject them under your skin, usually once a week. That's changing. In the summer of 2026, the MHRA (the Medicines and Healthcare products Regulatory Agency — the UK's medicines regulator, which decides if a medicine is safe enough to be prescribed here) approved two brand-new pill vers

GLP-1 Weight-Loss Drugs: 5 Myths You've Probably Heard (And What's Actually True) If you've talked to anyone about Ozempic, Wegovy, Zepbound, or Mounjaro, you've probably heard some confident-sounding claims. Some are true. A lot are not. Let's sort out fact from fiction using real research. Quick refresher: all of these drugs belong to a family called GLP-1 medications. GLP-1 is a hormone your gut makes naturally after you eat. These drugs copy that hormone to help you feel

You've probably heard of drugs like Ozempic, Wegovy. They're all over the news, and a lot of people take them to lose weight or manage diabetes. But how do they actually work inside your body? Let's break it down in simple steps. It Starts With a Hormone Your Body Already Makes Your gut makes a natural hormone called GLP-1 (short for glucagon-like peptide-1). Every time you eat a meal, your intestines release a little bit of it. GLP-1's job is to tell your brain and body, "He

Exercise is one of the most powerful tools you have to improve both your physical and mental health. When incorporated into your lifestyle, regular movement not only supports weight loss—it transforms your overall wellbeing. I always ask my patients what is a complete lack of movement? The answer is death - the less you move the closer you are to this state. Physically, exercise helps you burn calories, build muscle, and boost your metabolism. A higher muscle-to-fat ratio mea